他最喜欢的科目是什么用英语怎么说两种方式

"What is his favorite subject?"
"What subject does he like the most?"

The two questions are asking about the person's preferred academic topic. Both are grammatically correct and commonly used in English.

Examples:

"What is your favorite subject in school?"
"I heard John is really good at math, is that his favorite subject?"

中文翻译：

"你最喜欢的学科是什么？"
"听说约翰很擅长数学，那是他最喜欢的学科吗？"